Historical brief · 2026-11-11

Kyorin pays $140M for Japan rights to Edesa’s respiratory drug

Edesa Biotech has partnered with Kyorin Pharmaceutical to bring its late-stage respiratory drug to Japan in a deal worth up to $140 million. Kyorin will handle all local development and commercialization costs, while also gaining a first refusal right for other potential medical uses.

Source image · Fierce Biotech

Edesa Biotech has signed a licensing agreement with Japan's Kyorin Pharmaceutical for its anti-TLR4 antibody, paridiprubart, aimed at treating acute respiratory distress syndrome. Kyorin is paying $12 million upfront and could shell out up to $134 million in milestone payments, alongside royalties.

Paridiprubart previously showed promise in a phase 3 study involving COVID-19 patients, prompting Edesa to broaden its focus toward general ARDS. Recent exploratory analyses also suggested the drug could help patients suffering from ARDS and acute kidney injury simultaneously. Kyorin will fully fund local development and plans to leverage its existing respiratory expertise to push the treatment forward in Japan.

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